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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43501e12b255c3af09af69a2612ee087f7662e826d4da5672d8c718fc4e94a98' 
  AND token = 'rkrvDrLII/RQP7EO4XrMKRokrZ+PhukQFdVd66gQUw8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}