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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80df744f737bc6b9902d805edc1abd57c5d8a7a0987fcf3f5da9ef1e204b2048' 
  AND token = 'nwvGk6nqxhk5vzayc+YHfs5+0KyAYtXY+jkO7qPJvuk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}