SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a467e262ea4746d8c38decffbe8e7e690bf4755cb5823a776c045380704a10f' 
  AND token = 'lVFnEXXtSf4xs3RaVv3RdZbD7FGLMvo8nfhGSsg1m5E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}