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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b0f74c6afeee623e935f6e8df4b6800adffda54357071b46dfe9a4a1062f313' 
  AND token = '1hW6aJ3SBC98wUT50BeNWAXtOqh6EMTCCIXGNPpti5s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}