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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5e66d3ad5954c995020975fe1d5bcffcf3d41e809771f424bd9e4030be07b0c' 
  AND token = '8xoZ3tusp8tY9jDhLsV33t8C9pjuIU5MmC3Dnvfjchw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}