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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12a225f9529a71bf4750c2c26edd80bb123b4eceb30ca7d930aef59212d1bd4a' 
  AND token = 'fhiakl4/oDWQBVpmfMU6+yzBN5k3Ov/ncN0+/M8IU+Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}