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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e362268f391db7a45c2b50aee33516d46a84e50a44b7abc5278df89c644f9d5' 
  AND token = 'uBOHSfMUgemIMn3mc6cEtKT1cfDfL/yKuUo1+uAytZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}