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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7572c995fb2035dfedd750b7cb1c05bf2db187a7a080d39a62345c1741c3bf97' 
  AND token = 'vHTV5FkV3Gau+zptYLXFR8bWARvR+GP4PB56K5daExk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}