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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f878890b7b723f280347376696f7f574ac075f964efe575c01e1c2caa414f21' 
  AND token = 'EcC99x4G4pBfqKdkzTyX0m8JZ+wqNoIj9Kb0bQ4zNNw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}