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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16178e1f16510f06f7aae2faf60eb02c7ca191948a5d23e9914e8b6f959f3918' 
  AND token = 'pFSMxBbjanUMa5tJ5LId/iT/X22SFy5AKXHlnlD6HEo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}