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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c81239a7ee60a52b060b3a033d43a233e258e8a1c24c122daf38d4af96cc412' 
  AND token = 'Ioc7Mjb/VjYe6q7ClWc4e4I1o8GuTE9ZygH0gKY9Ie4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}