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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53badfa2ec796a292f2459bf7f341a0a1958a1661fa44e8b04a8d70449f04638' 
  AND token = 'Po8Kk6QZwJkT/LjoKRi312zUn21qBbz1e2Sh3Fi/5EQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}