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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8605e63ee0a25343c09386e749f9c038c9a25f2acee6945b3915289dac21bd4a' 
  AND token = 'PQJS25yWQ+qp7LGz/ZoEH8f8quGUQP58oE2ySZ7d7AM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}