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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed0fe9e043a1921ad8fa7fbe872b5e95632785d73e5f0e94b077844b9c02a411' 
  AND token = 'dRB3Z9FlpT7+0nfXJvX9v9d8lU+TFPPU6mM1GkF11v8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}