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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59a5838c3c6661e30e7326911986efcb54b3abf5e5817961571763a40a4adb12' 
  AND token = 'Px7e69h47dOavCqwK+amC/pmgvIlbKxao/hhSI4gH0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}