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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '782e1e862aa6b7d65812518b8bf99210977fda8be15cd05bd61ddccc57cb5b54' 
  AND token = 'gghK9ZhGZFLuM+t4EdnC9v4W0/7RMs/Z+Xjqs202sOo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}