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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4355c0a94ecf376913d00e432d9d20f68169276851dd193fa8a9b83c8a954a4c' 
  AND token = '/azhMH4xyIcgerOQk3y/1ch0utkvr2LZCE/p1pwZ0DQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}