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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '478f74d121d656f82c1cd2d7ceb9d1904d1ee9bdc7d1d962dd9c3595799306aa' 
  AND token = 'IvPMHdf28CCoknHtyzN1f6/Wr2W1Rp3PbGQEmBwqy/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}