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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e53d4beab27c98dc1f8780e447141b3c8e77b97ec5005996ebacd35d7de5c8f6' 
  AND token = 'Agk+TQOAdDvup6Pcc0hvCZ5E0eSE2rDYRUlaGBzBurc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}