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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a99e28f475638d7488c1a4638a2df950477ddca26efebecf954a0d110e27ab3c' 
  AND token = 'CE7ArtgL26M+GZIUbHMkd/4f4zm6MtLa1lZ23AR5IEM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}