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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '288a305c6841b041798c96dd6d17c77722e6cad846f2910c2cb92ef94297f72e' 
  AND token = 'YGzv4RSa+hdvG35BZsps29M/GDE2S2OtSlbcwsdOjVk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}