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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7144187a4d12a3ce8b6335c71fb472ffb42449ef09b2188d3154e375906e16a5' 
  AND token = 'qP31977MEmUcDcYrMvyJuO2WmF0tXOG2OM0NW/4dnyU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}