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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42a63fead0edf2b2ff32d231d30a72b021e8d7b9da72700cbc9a6bc5a436751a' 
  AND token = 'MUH2T0GNZ0pFH7OaZf7DrBuoQK0HoZx9fDBFa+DplJw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}