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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60b18f9a0d19fa6280d9d34aedcd96b00f0b3e348dabdae7bf2f9f243caab408' 
  AND token = 'PXTFbMwZ+qBUAgMaWaDLlVBocQu/qcI9euHahWzWSYM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}