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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e487d1e8623798c86dffd9770fb3fb0740e7005e7230e79df093ad8428fc04a7' 
  AND token = 'fQoId2a37PFTI8oUNSOuzGDPekDrQj7XJmUb/RpVtiY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}