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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80359777167239a548edeafd4f1a224a9ad6f20e7f8532671e401a3756c95eb7' 
  AND token = 'mYdyvRg04iT0xsx9zXsc7pqLJto6Tq3V/86MYckUSyQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}