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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6216fb0efdf2221bf92dc08d6fc82a3d251fae4485419b2ae7deb0aedbc07405' 
  AND token = 'ZfLs+xaGDHsP7i7ePBjAVC0rgo6q+k/q5SDu4UmHX/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}