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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c0b0a1a63387402ccceaa6aa1b78b2f3ede349e72411b2fdb8855e10fb5117a' 
  AND token = 'R+K0woomGpy9rPAvlwiNQVMSQvx7S1W1/rTFnbNsiQU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}