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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64f296691cd5a39fac31b49da13cc769a51a30417213ba0e4a8e52d642282d7d' 
  AND token = 'u1lfB5LhiAOkfIL3T2zWSRBh6PhHIwyqpa0s39tsnFY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}