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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0b8c1ead8270562ecb0afa260b6fe2e4c6225085ec7e8142db124278d6cca0b' 
  AND token = 'OXOB2O3M4n7E6i26QDZPnhUr8uXq1jvZPXCSJOO6nQk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}