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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37a6681946928e6cf0643891ebcc90bc54c3c8019ea65f98fc06a3a3138f50c0' 
  AND token = 'dr3qaHu65IfqnNt8XGiI9q5NXTz5ksA0D4CQ8g9lQ/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}