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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10618a2ff7e7be58241c722a6030fe393eac83ee7e9b36b3a4b465ec761ee601' 
  AND token = '30atKaqK+vE0In9oHju5/tkwCN6gKts27S+VBFXSuCc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}