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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fe6ce32bd3c770ec33e20a97c77aa4b7bb9e0da3e217336d461206f4d0ea3f6' 
  AND token = 'dUPF7BAUdMR3OweG4uehrYHdiFw+LI26GyJ6ZRIUzSU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}