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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '165000313ccc7f935cc6b335fd8d9a841429f2b65ea5d8b9863d8e11ca7a3148' 
  AND token = 'zZ0dv4VdhoFPu2Gh1e3a3ZkUg3Q/r5knJVcOM7VE/ps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}