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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8d6909f4ec392403240b3c2455e7410146b7df027c3b74d453ee3da2ed12ed0' 
  AND token = 'pwpNw1PXCnhke2pvLmVtQ8+1+LVHnaKmamH0Xu47G3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}