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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb0dfbd631352dce518df0e159db830502ca79ab6ed4ec520f075ab069c89323' 
  AND token = '9Itd41HgOpcDlKN8cAaSRBDHjE1tUCPbVC/tpg4siNM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}