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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8d29111dde993feab8b508ee4421f321a9c8a5a955ca341b3c579e22ab49701' 
  AND token = '7GAmzn/aDWHkqeGenwggGOdWP+YUcrCWjtQM8Tk00MU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}