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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21c7e6feae011c981aeef2039e7d61d92f89e116b4ee1a98bb2b11278753e91b' 
  AND token = 'IIYk2rd5wXJKJ+Wq1MLnXbZwnGdZkqI3lbMW+/yUXUA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}