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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '815ad488c6b1b5228d561fb3b82cc0e51f79a5b9db2eb0c80842126b68c68602' 
  AND token = '+CuwGzOe6MoLIyXfDcLyBeZkTPIGB0NRMxtJjl8rCR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}