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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49b4adf4e14a7deb76e8f4cbb85037b44422a6214dfe433b3f94cf004c980b33' 
  AND token = 'XjYsMd8RZfWrKtxwPQhu7FdL7O5RcaJkHsEhE8iwiyk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}