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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '522314e0923af4b72f34f99bff1325161e875c3fbd9b7c5de4acdcd5bfb12974' 
  AND token = 'JFvJQM4Qs6OFuoQjw9Z/vQdpwhWpi7kLmT5pxN3p5vQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}