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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78ab0ca8907397613682f583a35c3e6176c07ef84484a06ad09f58036cac150a' 
  AND token = 'wCtmjjSOlH8+Xz3RW4Z1mKdhRjyLye84dfgJ9HdVORo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}