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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3281cf3452ee6fc85856c9d7335e452bb10cd8dd49f808fec4bb1b03953e6322' 
  AND token = 't7YgxEQgOs9vLrvtDGOev4mLqNqGIbGW92bGwW2YMvo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}