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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61cd727a489d2f095a0e72a2d25b8a77ce58fe4025bcff2f1dc58327e06f3289' 
  AND token = 'IvwmaFondz/d158tZkE31gxciRwY9ckb0hwtIGw9+0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}