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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8e0435a330b33c64b3340a4f7463a7cb0a0551e1926745a2f239a3fb2c4172a' 
  AND token = 'XM9iJALbPBa3qTUHp0j2iJtELrIEkL1twsknAmix8zA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}