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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3579f1afba3b34bdde3a9f0b440cb649a4a9c08e01e22d817c25e7f08506899f' 
  AND token = 'ZdK0kznrR1gt3d+0AalxDOhB7yjNxUP4fiO0Sn70USw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}