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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4e54b94170eed824276494e99dcac1ed7a3eb3fdafbacd4b0b5891201fedb06' 
  AND token = 'h+e5ghWXCnN/Ae8tl2FO1P3y5sJ5KOLWBsEM6UhhYuk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}