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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '243d450f38a58c554789b98ab825a4825a264f8fa1ac49967d1c9c8b85f41570' 
  AND token = 'l/yQFdjYMo07sEnVnzSFkaW7dqXYcBI65bUu+0bgHhg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}