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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a151c45aabdc66d9642fbddb28cdda5ba57ee016b521af8fe26973bc5a2c86b2' 
  AND token = '6WATfaxo+065UvBhp7PJD+zLopXyg5fuqvvyDl9MUrU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}