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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad42366f4db37f03106b20a04a9999089e03daf2275927a7c25796c4f2b6446e' 
  AND token = 'X1jjYc2hhcgq3VbwsfkkFJFygxoJzF5im+0DOsr4TjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}